Explain the clinical meaning of solitary tiny brown pigment topostabile located at topographical area - 230' and indented closed lacuna penetrated to the border of the collarette at 220' in physical & psycho-emotional levels. Take note that the sign at 220' is not a liver lacuna !! Liver sign is determined by brown pigment, transversal, radial furrow, local indentation, sign at pupillary zone - Embryological & Kreb's Cycle, accept 'Lacuna". Never show Liver sign as Lacuna !!
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