According John Andrews, the embryological sign at 360' signify as hypothalamus stress and it demonstrate one of the most important iris sign, It will take priority over all other iris signs and it indicates as follow:
a) Impaired adaptability in all situations, such as the genetic weaknesses of thyroid, liver, gall bladder, pancreatic and gastrointestinal imbalance which found in the layers of IPB structure and pupil flatness.
b) Need for longer treatment and recuperation.
c) Greater intensity of detrimental reactions.
d) An elevated sensitivity to stress.
e) This minor ray at pupillary zone - 360' also associate with Pyruvic Avid imbalance that indicates family medical history and tendency to diabetes mellitus and hepatic steatosis.
* Observe a defect sign at internal collarette border - 140' correlate with Succinic Acid imbalance indicate family history and personal predisposition to diabetes mellitus.( Take note : Space Risk 14 & Inferior Temporal Flatness )
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