Crypt at Internal Collarette Border - Rx

In Modern & Advanced Iridology perspective, the crypt located inside border of the collarette or pupillary zone-25' manifest as a multidimensional sign and can be analysed as follow:
a) Classical views as potential disturbance in transverse colon.
b) Pineal gland disturbance as in embryological approach.
c) Krebs Cycle relates to Coenzyme A imbalance.