The multidimensional approach indicates family history of cardiovascular risk or predisposition to heart disease problem amplify by hypertrophy of the IPB. ( Take Note : Combination Approach - Pupil > Inner Pupillary Zone > Border of the Collarette ) :
a) Pupil Flattening - Lateral Temporal Flatness - 250'~265'.
b) Embryological sign - 330'
c) Closed lacuna attached on the border of the collarette - 275'
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