Multiple Lacunae Around the External Border of the Collarette - Lx

General genetic weaknesses for this polyglandular structure type:

a) Disease originates in the endocrine system

b) Thyroid & adrenal glands weakness

c) Diabetes Mellitus tendency

d) Pituitary gland weakness

 Which lacuna is set priority to analyse ? Could you find which iris sign indicate family history of spleen deficiency ? Could you differentiate the physiological weakness where lacunae located at 121' & 135? Could you identify which internal lacunae - 65', 82' & 115' that  it weakness is correlated with the lacunae at external collarette border ?